The study investigated the effect of utilising chemical compounds from selected indigenous herbs for theatre and film makeup formulations in Akwa Ibom State. Laboratory protocols were used to analyse the phytochemical constituents of some selected indigenous herbs like camwood, plantain stem juice, hoolahenna, okra, and palm fruit to ascertain their necessity for theatre and film makeup formulations in order to reduce the high demand for foreign-made cosmetics. Findings from the study revealed that camwood contains saponins; plantain stem juice contains flavonoids; hollarhena contains steroids, glycosides, tannins, and phenolics; okra contains flavonoids; and palm fruit contains carotenoids useful for cosmetic production. From the study, it was concluded that indigenous herbs should be maximised as an alternative option in the production of theatre and film makeups.